Cart
sales@molnova.com
TC-S 7005
CAS No. 1082739-92-1
TC-S 7005( —— )
Catalog No. M26838 CAS No. 1082739-92-1
TC-S 7005 is an inhibitor of Polo-like kinases (IC50s: 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 158 | Get Quote |
|
| 5MG | 267 | Get Quote |
|
| 10MG | 399 | Get Quote |
|
| 25MG | 646 | Get Quote |
|
| 50MG | 888 | Get Quote |
|
| 100MG | 1197 | Get Quote |
|
| 500MG | 2403 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameTC-S 7005
-
NoteResearch use only, not for human use.
-
Brief DescriptionTC-S 7005 is an inhibitor of Polo-like kinases (IC50s: 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively).
-
DescriptionTC-S 7005 is an inhibitor of Polo-like kinases (IC50s: 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively).(In Vitro):In human SR fibroblasts, TC-S 7005(1 μM) obviously causess myofibroblast differentiation and decrease fibroblast proliferation rates .
-
In VitroCell Proliferation Assay Cell Line:Primary human SR fibroblasts Concentration:1 μM Incubation Time:7 days Result:Markedly induced myofibroblast differentiation and reduced fibroblast proliferation rates.
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetPLK
-
RecptorCBP/p300| Cereblon
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1082739-92-1
-
Formula Weight359.385
-
Molecular FormulaC21H17N3O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (347.82 mM)
-
SMILESC[C@H](Nc1cc2c(noc2cn1)-c1ccc2OCOc2c1)c1ccccc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4.
molnova catalog
related products
-
Tebanicline
Tebanicline (ABT-594, Ebanicline) acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.
-
Cyclapolin 9
Cyclapolin 9 is a selective, potent, and ATP-competitive inhibitor of polo-like kinase 1 (PLK1) with an IC50 of 500 nM, and has not shown activity against other kinases.
-
Epimedin A
Epimedin A has anti-osteoporosis activities in vivo.
