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TC-S 7005
CAS No. 1082739-92-1
TC-S 7005 ( —— )
Catalog No. M26838 CAS No. 1082739-92-1
TC-S 7005 is an inhibitor of Polo-like kinases (IC50s: 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 158 | Get Quote |
|
| 5MG | 267 | Get Quote |
|
| 10MG | 399 | Get Quote |
|
| 25MG | 646 | Get Quote |
|
| 50MG | 888 | Get Quote |
|
| 100MG | 1197 | Get Quote |
|
| 500MG | 2403 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTC-S 7005
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NoteResearch use only, not for human use.
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Brief DescriptionTC-S 7005 is an inhibitor of Polo-like kinases (IC50s: 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively).
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DescriptionTC-S 7005 is an inhibitor of Polo-like kinases (IC50s: 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively).(In Vitro):In human SR fibroblasts, TC-S 7005(1 μM) obviously causess myofibroblast differentiation and decrease fibroblast proliferation rates .
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPLK
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RecptorCBP/p300; Cereblon
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Research Area——
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Indication——
Chemical Information
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CAS Number1082739-92-1
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Formula Weight359.4
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Molecular FormulaC21H17N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESC[C@H](Nc1cc2c(noc2cn1)-c1ccc2OCOc2c1)c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4.
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